High throughput transepithelial electrical resistance (TEER) measurements on perfused membrane-free epithelia
نویسندگان
چکیده
We present an instrument for simultaneously measuring TEER in up to 80 perfused epithelial tubules on OrganoPlate. The sensitivity, speed and ease of use enables screening during formation, drug exposure inflammatory processes.
منابع مشابه
Freshwater Sponges Have Functional, Sealing Epithelia with High Transepithelial Resistance and Negative Transepithelial Potential
Epithelial tissue - the sealed and polarized layer of cells that regulates transport of ions and solutes between the environment and the internal milieu - is a defining characteristic of the Eumetazoa. Sponges, the most ancient metazoan phylum, are generally believed to lack true epithelia, but their ability to occlude passage of ions has never been tested. Here we show that freshwater sponges ...
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ژورنال
عنوان ژورنال: Lab on a Chip
سال: 2021
ISSN: ['1473-0197', '1473-0189']
DOI: https://doi.org/10.1039/d0lc00770f